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Dry Stimulation Mixes for Immune Functional Assays. Lipopolysaccharide (LPS), a constituent of the membrane of gram-negative bacteria, represents a pathogen-associated molecular pattern (PAMP). Brefeldin A blocks Golgi-apparatus-mediated secretion. A mix of these 2 compounds strongly activates cells of the innate immune system expressing LPS-recognizing surface receptors such as monocytes and traps newly synthesized biomolecules (e.g., cytokines) inside the cell, indicating the capacity to respond to microbial pathogens.
The DURActive stimulation kits contain optimally dosed physiologically active compounds provided as unitized single tests in 12x75mm tube format.
|Specificity||Lipopolysaccharide / Brefeldin A|
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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS
The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.