IgM Antigen

The anti-IgM antibody binds to circulating IgM as well as to IgM antibodies bound to the FcμR. The FcμR is a transmembrane single sialoglycoprotein of 60 kD with O-linked oligosaccharides. It contains an extracellular Ig-like domain homologous to two other IgM-binding receptors (polymeric Ig receptor and Fcα/μR) but exhibits an exclusive Fcμ-binding specificity. Unlike other FcRs, the major cell types expressing FcμR are adaptive immune cells, including B and T lymphocytes. The FcμR can be expressed as a cell surface activation antigen throughout the pre-B and B cell stages in differentiation. Receptor expression is not directly linked with IgM production, as both μ- pre-B cells and isotype-switched B cells may express the FcμR. The FcμR is thus the third member of a family of Fc receptors expressed on B-lineage cells, and its preferential expression on activated B cells suggests a potential role in the response to antigens.


 Clone: SA-DA4  Isotype: IgG1 Mouse

The SA-DA4 monoclonal antibody binds specifically to mu heavy chain of Human Immunoglobulin (IgM).
 

 

Explore Beckman Coulter IgM Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
RUO
SA-DA4
50 Tests
Buy
RUO
SA-DA4
50 Tests
Buy
RUO
SA-DA4
50 Tests
Buy
RUO
SA-DA4
50 Tests
Buy

Product Line Specifications

Format Liquid
Specificity IgM
Form APC
Clone SA-DA4
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B30654

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents