Helios Antigen

Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice.


 Clone: 22F6  Isotype: IgG Hamster

The clone 22F6 reacts with human and mouse Helios.
 

 

Explore Beckman Coulter Helios Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
RUO
22F6
50 Tests
Buy
ASR
GB11
1 mL
Buy

Product Line Specifications

Format Liquid
Specificity Helios
Form Pacific Blue*
Clone 22F6
Isotype IgG Hamster
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B49311

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents