CD95 Antigen

The CD95 (Fas or APO-1) antigen is a 40-50 kDa transmembrane glycoprotein. It belongs to the Tumor Necrosis Factor (TNF) superfamily and contains three cysteine-rich repeats. This cell surface molecule mediates apoptosis (programmed cell death). CD95 antigen is expressed on a substantial proportion of peripheral blood CD4+ lymphocytes, CD8+ lymphocytes and B lymphocytes but on a minor proportion of NK cells. It is not found on platelets or erythrocytes, but is expressed variably on granulocytes and monocytes. CD95 is strongly up-regulated on activated T cells, B cells, NK cells and thymocytes. Moreover, it is widely expressed on cell lines of T, B, NK and myeloid lineages. Most other tissues express CD95.


Clone: CH11   Isotype: IgM Mouse

The CH11 antibody in vitro induces apoptosis in some CD95 expressing cell lines.

Clone: UB2 Isotype: IgG1 Mouse


Choose a CD95 Model

Product Line Specifications

Format Liquid
Specificity CD95
Form PE
Clone UB2
Isotype IgG1 Mouse
Cross Reactivity Carp
Target Species Human
Item Specifications Referenced IM1739

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents