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The CD65 antigen is analogous to the carbohydrate structure(s) recognized by CD15 antibodies. CD65 is a type II chain fucoganglioside involving the oligosaccharide sequence: Galβ1-4GlcNacβ1-3Galβ1-4GlcNac(Fucα1-3)β1-R. CD65 has been suggested as the CD62L ligand, and it has been hypothesized to be involved in the extra vascular infiltration. CD65 is normally expressed on neutrophils, eosinophils, and basophils, on a monocyte subset and on a fraction of CD56bright NK cells. It is not expressed on lymphocytes. CD65 is also found on the membrane of adipocytes and on thymic epithelium but it is not expressed by mastocytes. In myeloid ontogenesis, CD65 seems to be expressed later than myeloperoxidase (MPO).
Isotype: IgM Mouse
The 88H7 antibody was re-assigned from the CD65s to the CD65 cluster during HLDA 6.
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.
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