CD49d Antigen

CD49d is the integrin α4 chain that non-covalently pairs with CD29 (β1 chain) to form the very late activation antigen 4 (VLA-4), or with the integrin β7 chain. CD49d is a transmembrane glycoprotein of 145 kDa devoid of disulfide bond. Complexed to β1 or β7 integrins, CD49d is not only involved in cell adhesion to fibronectin and vascular cell adhesion molecule 1 (VCAM-1), but also in intercellular leucocyte interactions. It is expressed by monocytes, lymphocytes, eosinophils, thymocytes and Langerhans cells.


 Clone: HP2/1  Isotype: IgG1 Mouse

The HP2/1 antibody blocks the interaction of VLA-4 with VCAM-1. HP2/1 was used as a CD49d reference monoclonal antibody during the HLDA 6.
 

 

Explore Beckman Coulter CD49d Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
ASR
HP2/1
0.2 mg / 0.2 mg
Buy
ASR
HP2/1
0.5 mL
Buy
ASR
HP2/1
0.5 mL
Buy
ASR
HP2/1
2 mL
Buy

Product Line Specifications

Format Liquid
Specificity CD49d
Form APC-Alexa Fluor* 750
Clone HP2/1
Isotype IgG1 Mouse
Cross Reactivity Indian Rhesus, Bovine, Ovine, Caprine, Equine, Canine, Feline, Mink, Llama, Rabbit, Carp
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B16893

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents