CD19-APC

IM2470

The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. CD19 is involved in the regulation of B lymphocyte development, activation and differentiation. This molecule is expressed on all normal B lymphocytes including pro-B lymphocytes, but is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes.

Specifications

Target Species	Human
Specificity	CD19
Other Names	B4, Bgp95, CD19
Fluorochrome	APC
Regulatory Status	CE
Size	100 Tests
Format	Liquid
Flow Product Line	IOTest
Clone	J3-119
Isotype	IgG1 Mouse
Clone Description	In vitro studies show that the CD19 antibodies have an inhibitory effect on the activation and proliferation of B lymphocytes. They also inhibit the B cell response after co-stimulation by anti-immunoglobulin and interleukin 4.

NOT ALL PRODUCTS ARE AVAILABLE IN ALL COUNTRIES
PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.